Embryo implantation - coordination of maternal and embryonic adaptations

Embryo implantation after assisted reproductive procedures and maternal thrombophilia.

BACKGROUND AND OBJECTIVES Women undergoing assisted reproductive procedures, such as in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI), fail to achieve pregnancy in approximately 70% of cases. Postulating that among the possible causes of failure of embryo implantation might be an impairment of the uteroplacental circulation due to hypercoagulability in the mother, we inv...

Expression and function of matrix metalloproteinases and their inhibitors at the maternal-embryonic boundary during mouse embryo implantation.

Gelatinase B, a matrix metalloproteinase (MMP) of high specific activity, is highly expressed and activated by mouse blastocysts in culture, and inhibition of this enzyme activity inhibits lysis of extracellular matrix (Behrendtsen, O., Alexander, C. M. and Werb, Z. (1992) Development 114, 447-456). Because gelatinase B expression is linked to invasive potential, we studied the expression of ge...

Kisspeptin, unexplained infertility and embryo implantation

Objective The primary objective of the study was to compare baseline KP levels in females with different causes of infertility and then correlate it with the risk of failure to conceive, preclinical abortion and pregnancy after intracytoplasmic sperm injection (ICSI). MaterialsAndMethods AA longitudinal cohort study was carried out from August 2014 till May 2015 recruiting one hundred and twent...

Hysteroscopic Subendometrial Embryo Delivery (SEED), Mechanical Embryo Implantation

Background A major hurdle to improved in vitro fertilization (IVF) success rate is defective endometrial receptivity and implantation. Various techniques have been advocated to increase implantation while reducing side effects. Currently, embryo transfer (ET) is performed blindly without direct visualization. As such, we sought to develop a technique utilizing a flexible minihysteroscope with a...

Human implantation Implantation of the human embryo